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Ultram ER 300 mg medication is used to help relieve moderate to moderately severe pain. Tramadol belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.

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Read the Medication Guide provided by your pharmacist before you start taking tramadol and get a refill each time. If you have any questions, ask your doctor or pharmacist.

Take Tramadol medication by mouth as directed by your doctor, usually every 4 to 6 hours, for pain relief. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).


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If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start Ultram 50 mg medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully. The maximum dose is 400 milligrams per day. If you are older than 75 years, the maximum recommended dose is 300 milligrams per day. Do not increase your dose, take the Ultram ER 100 mg more frequently, or take it for a longer time than prescribed. Properly stop the Ultram ER 200 mg when so directed.

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Pain medications work best if used as the first signs of pain occur. If you wait until the pain has worsened, the medicine may not work as well.

If you have ongoing pain (such as arthritis), your doctor may also direct you to take long-acting opioid medications. In that case, Tramadol Hydrochloride 50 mg medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as acetaminophen and ibuprofen) may also be prescribed. Ask your doctor or pharmacist about using Tramadol Hydrochloride Extended-Release 300mg safely with other drugs.

Suddenly stopping Tramadol Extended-Release 300 mg medication may cause withdrawal, mainly if you have used it for a long time or in high doses. To prevent escape, your doctor may lower your amount slowly. Tell your doctor or pharmacist if you have any withdrawal symptoms such as restlessness, mood changes (including anxiety, trouble sleeping, thoughts of suicide), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden changes in behavior.

Talk with your doctor if Tramadol Extended-Release 200 mg pill stops working well.

Though it helps many people, WATSON 466 50mg pill may sometimes cause addiction. This risk may be higher if you have a substance use disorder (overuse or addiction to drugs/alcohol). Take this pill exactly as prescribed to lower the risk of addiction. Ask your doctor or doctor for more details.

Tell your doctor if your pain does not get better or if it gets worse.

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